In the 2016-2018 seasons, the average differential between home and road scoring margins using only home and home matchups, was 5.85 points per game. In other words, in games where teams played an opponent at home and on the road in a season, the average had a 5.85 point scoring margin better at home then on the road. Kansas was slightly above the mean at 7.35 which ranked them 139th, very much in the middle of the pack. As a point of interest, for that three season span, 24 teams had better margins on the road than at home. None of those were in the power 6 conferences. In 2019 KU has a home-away margin of 25.2 points. Of course that is largely skewed by the Texas Tech games but it is a data point. Even removing the Texas Tech games, the margin differential is 21.2 points per game. The 25.2 points per game ranks 5th in Div. 1 for 2019. Interestingly, Texas Tech ranks 6th with a margin differential home and away of 24.6. If this holds up, you have to like Iowa State's chances of beating them in Ames. Here are KU's Home/Away scoring margin differentials by season
2016 -- 11.88
2017 -- 5.22
2018 -- 5.44
2019 -- 25.20